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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2dfaffe29818f445c290ed0b8fa5e6753cb0373bc208016dfd72176ef017878' 
  AND token = 'Xpr+nh+FfoJJ31Ymp0Z5ybaarDr4kyuGrsA4Xaarig0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}