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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec21ab2398bf96c8561ed978be2c72fcd0e2bcbeff1e0e79a983edf80a9fe799' 
  AND token = '/UKDeS/usPeNG2NZoToTfrxBD01aaRGsQlh89/9mUhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}