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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4874e63e8a953037095b3aa6be031e3fc9c6de954018b9caad50d2ba15a46df2' 
  AND token = 'cCHqVuPPOdjQyX0SFZCTH3xTbkpg/D6WyFYNcv+PAqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}