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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c222e01d9b3e8a6c95ed574b16071c3bace3931c8388897f4b261b3858d1512' 
  AND token = 'Fta66EM8+3ieA/Ie3ka804JOdrNuy2SOuHfsoYzR4U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}