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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf3de4b5ea80a635bdf0a8267435b7e33eb8ce32f0cb6dc0bb38024c72f08d16' 
  AND token = 'oHjhHSPtbO8nCRHE5l2qtSm+bmXYLCDxKofoyfnNA/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}