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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d9acdc547694d815a2b37c7b0123c7fc49285ef580c8bd61213a9a83f224add' 
  AND token = 'yAs5T7sz6BbVEYpDqws4Lr5KfY9vEdh5X79Oh5TyqaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}