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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d86db05974b1fe82b8adb6969ba3ca85f8ee0be7a20901e88c69b5d77e3d10' 
  AND token = 'HrU3UUrPX69YbXqrNF+B9LoLTQjncsAhJ9gjQAL1ppw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}