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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b69e32f0c45a52caa01b247d39c68d94c365760549598d6143415c1235d4c5' 
  AND token = 'Kzk1KRyZH4zTXW21MhI7z7RWdc7AiG7CdcAn+EcOmxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}