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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca0b3dd59f95263edfb55d0cd85018c13f6df17d44df25231e7a069792e6363' 
  AND token = 'IWPS5aLISytmnmv6N7PMsIj4D8xW7Il7EI5OiTPYWa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}