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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b09091366e21d4fd24d2b9b6688f17a37d70ba06770212325c2bda5c0dd80edb' 
  AND token = 'iQ/7jv/uqbPGy1Iq2ucz1GMUCDe3+fvHBPwMqpmDI3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}