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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ff9226cbe71f1a59cbdaa9bea01c0de18974679ee974b9009136e11bbcd2e27' 
  AND token = 'XwJIRMPJSBswyRqH8o97A8hX6guXdJbPoT2F3/VOyW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}