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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '026220a297c5523c0253c7b8fd7cb7d9a287ab5c57b23c0dfc0bdcf2cd039015' 
  AND token = 'BwrDJMT3aa2Ca8wZS9Lo3++y7AcWAWeO8U8Qq+i8WiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}