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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a1a49f73acd88a97290b6c6465260723735e26b41c3fdb414df412b87a01551' 
  AND token = 'vVAl9LoOzGB/oMy4HOz/SkECrq0kgTlDk1fPE/c044k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}