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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c1183c5d9d1bf019991497621a6aa0076448d172a6da748a878925cbce24232' 
  AND token = 'n2IMG/1tMKdTGuxAXb1wctlrjK1LiHnXrcsNbbE5tvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}