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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d881eb7b57573843c7abaa92ea60490819a0f6cdf68b7236429bcdd19f0579a' 
  AND token = '77IE2XUAP3c/dLfx3xL6gX6iA2KnOaOcO7eonb60iws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}