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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea1f8d7429c0219e1eb4fbd1bd0ec1c476d5e4bbe06c129e12e330eaa4a2201' 
  AND token = '/FtcK7cErJjXD4/Furg/IJhR+PAPMSwD5FWmXbVC1Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}