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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '063a065ea0f53e192a98760d21add8bdee4ea6d1123677e1260e7a97fe407302' 
  AND token = 'RQgRzWyJEdOlX3yCtvjr9UnbWtCon26VKJ+F1JMNYb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}