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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1dcf480d8e73728e31c0e873d88f591df840c0b551c94554bdec050a8810a1a' 
  AND token = 'auZPrvQ6BBfQx2IATI/6V1e3WjDM5IY7kmyc1WXYbsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}