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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7dac065e68d964c8ea1b224a44ab916b1c6102c68ad27f862d19377d768f199' 
  AND token = 'frIf1wZ8O3k2y0II1nLDPG7T5KiG28whIOO8XNbwfNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}