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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c76c7eb150fb9174dc0cdb888159bb273d4901130e1eb47804dd49cd485b50d8' 
  AND token = '+u2cwswvAgq0TOxd+hrp+kxcIaq1iYivldtfvKHn2LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}