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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b1443fa708b23e66a73dd55e4779236c8e2c9ba9d8599757084a7b0318afad' 
  AND token = 'cVAkOzenmvkMLmqh9pQDtMa9Q/whpxqD9rFalwJnxRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}