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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c94e0c0ceb1a86430b04a5cbce26c2d43a63c41fcb30a22e7564415c0be528e' 
  AND token = 'jagyvUH3Aln/rmzfwVp7T8SEEMjLhhmwzzWE33iH3aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}