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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3575ed0c46140d0ae051f4bcd96fc018dec1ed06e3c6084406b4488fa3c4a2fb' 
  AND token = 'fPxCUF+LohQ3vUAFuQf53CVhtUyObE+gvlLpgTpGzbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}