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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '870620683edf91da0aa19a89dac462479ff7cc5e02a571c5dfa11c84114d04d5' 
  AND token = 'Jd9zJEssTFuVw/8pPSEFYa0G0jbSfid6euDqlwJ0Cdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}