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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e04ea3fe0b5fc97e261a087b7d37e6f67f6147344f3790455c93b45886ef43' 
  AND token = 'OOzrePhf+OOtkXN2VVGJnqQme3W1ysIjGsTdE7TiAFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}