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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a065563ce81f85e65a5b361342a0af73e5bec97fb2d300702e6ef7d5ab23e5' 
  AND token = 'GDbQZByKPFGRhiVIOrD3pNIhZ/5HfCe9ww1PZIZVox0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}