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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6177c3f743467f9d8f19ca8fb6370cd9695da8b46db805b3aae27703b725599' 
  AND token = 'ZTyHsRTPj0eQX1VHNDpq4bZT4J82BtgD4BRsxXC8euY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}