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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0abf36f34bab0df5a204f3a1d2552d1c64e54a2e7e120d651e9911424fcbb5' 
  AND token = 'NRvk9NUW8+yIYpK1d6Gq1fnrcSL1I24CprWJioCzKmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}