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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b8669c272a4a45fbe5c783d7c819177a9c54ad81e0b8d16faf80251287a724' 
  AND token = 'ugdAU1DOos4OC4uZbefYBBoBkRVsOq/N+sGkSqpp01w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}