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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3847e62ca95cfa2d8faf996c113fe23f1fee6754372d52447fc3e0eb3882a84e' 
  AND token = 'SUg4eqzSOcHIKeQlPitiCpY5EGnfFjtVPAMGhtRCpL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}