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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b2d9c27c38ef96f5ab30bd947da5b6a77ea0aac9071df6253bd3c5838644f8c' 
  AND token = '7rlUGuSmvRhTnAT+1OM8Uu2S5hAaMWuZV7/tOS57qHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}