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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '497befbf183fbf8e422549a39e6b6c1a4c1bcf3939e472a3613e7c017e48a385' 
  AND token = 'nLKy9OF6Mm15SSNVp4rKjGbV8gb/HXC302GJCV+RdGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}