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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '785286b6b445ef324bc5dabe740e5cc2f38343224b4927d143b863365a4b5a9f' 
  AND token = 'fZRaLTLkJzRHdQT/gJPNO2VZTIMmldLJHU/DI2RlD2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}