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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2e4787feac1a6efc9a3e16b496e55686b4d396ee1e39dd9ed0dffd37f38e978' 
  AND token = 'ZcnghhXUrfuRLaVqRHGkimo6YfnRUs181GQ+x/F6Aoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}