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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b10b3ed6f5c4aa5c9a62877625ff680dbb458aa1715859c5bfc6632e6c4c023' 
  AND token = 'CVsfo4VaheOfwBdYXWhfKBjBMj1V0l2/n9nEM4vaOEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}