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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2228faf47e88ab0bdc93d85b728db5f8e5061cc86b3c363933ac2e0cc86c7a0' 
  AND token = 'rYjb664NPTtpNIKQkKHx0KHXr3SKbQqJBMm7k2MBIjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}