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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ce54b41395404b4023d03826858e4f6521b3a1e1765b67b351660e24ebb46f' 
  AND token = 'nYvEke/c+w8uNaq93fQaGdIbIgaexMvvnRztvtLaL7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}