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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91f89724920de43aad4e81ff1ab235c7240f80f8298b0c54c09f5e52f3e6eba2' 
  AND token = 'HHniYCC3f7R9rVC/Yyh9/e80ViKoFbG1dVikk7/OSVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}