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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24e397271d4980e3f13267f75ab2fc00b13f788948c7e121a3b9d65c51217dc2' 
  AND token = 'Pc1MZJNJwWAuHkHT+E6FbTMUMGIdx0MCtYc/4FDQI4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}