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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f491d99f79faf07126437008f9575ec132d998e1cd0139b690f1146cab989d9' 
  AND token = 'tn9b8IdVz3uwpL+kQsvYazs4xYUAyCQpKscMBvc3lO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}