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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c443a430f01501d9189f01b706b13e540e7b5b1a18e9568cf7fc8126154d998f' 
  AND token = '8mrI3lWhuRtNdOZTpjnkBJ4gdLijY4eHIH5YlN+VHzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}