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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21b08a70cd2e3fdef7beb99f56ac2df4f488d61f2193da01063e12a592a21a9' 
  AND token = 'SyST3nVFaLQRpLNnJ4x0i/EalxmkbT1VyRVt/Wvs1Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}