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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c79e1ce2a72ec3332bea4ad77ad1e2a6b55205a6a333a9fd25a84c242c22d120' 
  AND token = 'v+I5GCGgmCaYM4WOjp4GE9bazNg+nUAD51gD0zhAjNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}