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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b7a234aaf4e8f35b45134cf8f4aa1ede57a965cd85fb97f2da39c2da72da59c' 
  AND token = 'cNe/aemoC54RZeySCWmtM2CCa15krUvXp/3Ks/JFyVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}