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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54f0d447976b1cbd23c442fcc73be0f7ac1edf34720a821fe23ad15531343439' 
  AND token = '1Zr6gFeTl9HLJwguX2bqZUiL9IWsWXOwjDtMDB+A+3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}