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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcf7203fbb3298bbc6afb54c408afd45a372b7034b376f491f8cb604460e6196' 
  AND token = 'TpMO1RoFwGYFTxCwAdV+HXl4hgyEEclDxJ5kNeT0NUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}