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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2529f6f0db761c00d23f044513d2ab462984c2ff9d031ca3779cae9f5db6c7e8' 
  AND token = 'TC4HFwDyCvw9PN5bFoEFLW3tcmgPwDopgh7ESozj0fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}