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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2769a4357d8127bb331be152b75ccf6dadfa66c031d1fc6104b9aebf46e1b724' 
  AND token = 'i4hp8sfGEKDIOIny+rjJOi71EC0wb/o25wmWGH82Aj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}