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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0472cd3d4ffdf71f5497c71a1fa9ae83c0dc0b493aebc0d039f5029d670b9f28' 
  AND token = 's4c1ziyo+zf8CmLqkzk5MzsCAiwrJEZu2m6zuS+y9k8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}