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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cc9d369201eea72c490dc0307fddbbdde79cadc050a9b3dfa6a1ed8c05215f2' 
  AND token = 'bdKnVBUjLFTrec+EC8jn4lMnAc8lsNecXCWMy5j2e/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}